146 East Hospital DriveSuite 140West Columbia, SC 29169Google Maps
Charlene's Education
Masters Degree
Bradley University
College
University of South Carolina Upstate
Patient Reviews
Ratings and reviews are based on third-party surveys carried out by Press Ganey.
Average Rating: 4.8
January 31, 2026
Charlene Smith is very professional, knowledgeable and has very good bed side manners
January 31, 2026
Very concern if I was doing better
January 21, 2026
Ms. Charlene Smith is an outstanding provider. Very knowledgeable and excellent chairside manner.
January 21, 2026
Excellent as always!!
January 18, 2026
The NP was very thorough and answered all my questions. Highly recommend.
January 16, 2026
Charlene Smith is by far the nicest doctor I have ever seen in all of Lexington Medical.
January 16, 2026
Charlene is just great
January 14, 2026
My nurse practitioner, miss smith is amazing.I would recommend anyone that is in need of her surrogacy her. She was very knowledgeable with a lot of care and concern about your health and she takes the time to listen.
January 11, 2026
I love Mrs Smith. I feel that she truly cares about my health. She always takes as much time with me as needed. I never feel rushed.
January 10, 2026
The provider took the time to listen to my questions and explain the progression of Parkinson’s she involved me with the decisions to move forward. I highly recommend her from checking to leaving. The experience was very good.
January 7, 2026
Excellent experience. Charlene was personable, knowledgeable, and attentive. Answered all
questions and concerns thoroughly and in detail. Couldn?t ask for better experience.
January 1, 2026
Charlene Smith Neurology communicates very clearly, better than most medical professionals in my 68 years and I have experienced many. I am very appreciative of her!
January 1, 2026
Charlene Smith is the most caring and helpful NP I have had throughout the last 4 years.
December 27, 2025
My provider, Christine Smith was simply excellent, all the way around. She spent a lot of time with me, discussing my MRI results, and how my diabetes and diet affects any futures TIAs (mini strokes), going forward. In the end, I really like seeing Christine, and feel I get the very best care from her. I can tell she truly cares about my health issues, and keeping me healthy, along with my family doctor. She is a great asset to your medical team.
December 27, 2025
Dr
Smith (np) is amazing
December 25, 2025
Charlene is the best!
December 18, 2025
I trust Charlene Smith with my life! No doubts, no questions! One of the few providers who listen with both their brain and heart. She treats me with kindness, respect and wants only the best for me.
December 4, 2025
Usually very good. But NP rushed my injections. Causing them to hurt worse than usually and for multiple days. Also seeing random bump over my eyelids that I never had before in the 2 years of getting these injections before.
November 17, 2025
Care provider is had an awesome personality, is approachable and listens intently. Shares her thoughts but respects and welcomes your feedback.
November 16, 2025
Excellent visit. She made me very comfortable, explained why I was there and presented my next step with knowledgeable responses to my questions and concerns. I feel I will be in excellent hands on this (to me) scary journey. I am eager to begin this adventure. Thank you for introducing to this caring exploration 🙂🙃🙂
November 16, 2025
Ms Smith is very approachable and discusses options with me. I feel like she listens and cares. She really is a good provider.
October 31, 2025
Good visit
October 24, 2025
The visit was comfortable, professional and the various aspects of the information provided was extremely helpful and clear.
October 10, 2025
PA Charlene Smith is an asset to LMC Nuerology
September 20, 2025
Charlene was amazing. Went above and beyond to help.
September 14, 2025
Charlene provided outstanding medical care. She is a true professional.
August 26, 2025
The people were absolutely amazing!!
August 22, 2025
A wonderful experience, in the hands of caring professionals.
August 18, 2025
Excellent and educational experience
August 8, 2025
Charlene showed incredible compassion and genuine care during her visit my mom. She comforted me and reassured me that I?m not alone. I wish more care providers were like her
August 5, 2025
My provider was very efficient and detailed as we went over my MRI that I had received. I appreciate her descriptions used to bring her explanations down to.my understanding. Best medical group hands down. Highly recommend
August 1, 2025
Charlene Smith is an excellent Nurse Practitioner! Very knowledgable about me and my medical history. Excellent knowledge about her field of neurology and beyond. I highly recommend her!
July 26, 2025
Charlene Smith has been so helpful and sympathetic in the three years she has been working with me to identify my memory loss, determine its cause, and arrive at a plan. I feel lucky to have known her.
July 6, 2025
Very knowledgeable. Took my problems seriously. Came up with a course of treatment.
July 5, 2025
NP Charlene Smith is amazing. I’m happy to have her as my medical provider.
June 30, 2025
Charlene has always been compassionate and listened to my concerns
June 13, 2025
The care provider that I met with was simply excellent. She was very thorough and answered all of my questions at this time, before my prescribed MRI. Great job everyone!!! 😁
June 10, 2025
Charlene is a pleasure to come in for visits. She is polite, funny, and very helpful with any questions I have concerning my care.
June 8, 2025
I feel very comfortable talking to Charlene. She listens to my concerns and makes helpful suggestions.
June 5, 2025
NP Ms. Smith could not have been more caring and very helpful in dealing with my condition.
May 30, 2025
Charlene Smith, APRN is always kind, prompt, shows the utmost concern, and ensures questions are answered.
May 29, 2025
Exceeded our expectation our concern was well explained.
May 24, 2025
Charlene is the best. She listens and shows genuine concern for her patients
May 11, 2025
She has been better than the specialist that I was seeing in August he never done lab work
April 23, 2025
The staff was amazing!!!!!
April 13, 2025
Charlene is absolutely the best. She cares about all your medical conditions?.[...]
April 12, 2025
My practitioner was very detailed and very attentive to me and my needs.
April 12, 2025
Very pleased with care and support
About Charlene
Charlene provides comprehensive care in the evaluation, monitoring, prevention and treatment of cognitive and general neurological disorders.
Expertise
Charlene has nearly 10 years of direct patient care experience in medical-surgical inpatient care, emergency medicine and neurology. Her expertise includes evaluating neurology patients and formulating plans of care, medication management, patient education and ongoing follow-up assessments. She also performs skin biopsies, Botox® injections and sphenopalatine ganglion blocks, as well as reviews and evaluates imaging abnormalities.
Background
Charlene earned her bachelor’s degree in nursing from the University of South Carolina Upstate in Spartanburg and completed her master’s degree as a family nurse practitioner at Bradley University in Peoria, Illinois. Certified by the American Nurses Credentialing Center, she is also a member of Sigma Theta Tau International Honor Society of Nursing with additional certifications in advanced cardiovascular life support, basic life support and pediatric advanced life support.